Letrozole is a relatively new drug being used to treat infertility. It is primarily used as an alternative to Clomid before gonadotropins are used. Below, we will take a look at how Letrozole works and when it is used to treat infertility.‍

How Letrozole Works

‍Letrozole has been used in women with breast cancer for a number of years. It is classified as an aromatase inhibitor, and it interrupts the production of estrogen in the body. As a result, the pituitary gland begins to produce more follicle stimulating hormone (FSH) and luteinizing hormone (LH), both of which are used to stimulate ovulation. Several studies have examined the use of Letrozole for infertility. Most studies have been relatively small, and the results have been mixed. However, most of the evidence indicates that Letrozole is associated with a thicker uterine lining and lower miscarriage rate than Clomid, making it a strong choice in certain situations. In addition, studies show a higher birth rate as well as a higher ovulation rate with Letrozole than with Clomid, but the risk of side effects is not any higher.

Candidates for Letrozole for Infertility

Clomiphene, also known as Clomid, is usually the first-line treatment for inducing ovulation or superovulation in women. It is an oral medication which is effective in the majority of women. However, Clomid can not be used for an extended period of time because of its effects on the cervical mucus and uterine lining. In addition, women with polycystic ovarian syndrome (PCOS) do not respond well to Clomid in most cases. Letrozole is a good choice for women with PCOS. It is also a good choice for women who have not responded well to Clomid, but who are not yet ready to try injectable gonadotropins, which are expensive and carry a higher risk of side effects. Your doctor can help you decide whether or not Letrozole is right for your infertility treatment.

‍Side Effects

‍Letrozole for infertility does have some risk of side effects. However, side effects tend to be mild and temporary. Most side effects are similar to those seen with Clomid, and include hot flashes, headaches, and breast tenderness. Dr. Randy Morris would be happy to meet with you about your infertility. To schedule your consultation today, please click below and enter your information or call IVF1 at (630) 357-6540.