Some people claim that certain supplements, like CoQ10, can boost fertility and support success on your IVF journey. If you're struggling with infertility or going through IVF, chances are you want to do everything in your power to increase your chances of conceiving.  But what is the connection between CoQ10 and fertility, and does it help? Experts in IVF and infertility weigh in on this popular supplement and help address any questions you might have about CoQ10 and its relevance to IVF and fertility.

What is CoQ10?

CoQ10 is a naturally-occurring vitamin-like substance in the body. CoQ10 is present inside the mitochondria of your cells and helps them produce energy that's vital for cellular function. CoQ10 may also act as an antioxidant, as it offers some protection from free radical damage. 

Why Do Some Take CoQ10 During IVF Treatment?

As you age, your body begins producing less CoQ10 on its own. And, it's thought that fertility problems can be worsened or caused by low energy production in egg cells, or free radical damage to the cells. Therefore, CoQ10 is often taken as a supplement by those undergoing IVF because of its role in the cells. Proponents believe CoQ10 supplementation may improve fertility and increase the chances of getting pregnant. 

What Does the Research Say About CoQ10 and Fertility?

This might make sense in theory, but what does scientific research say? 

Studies have been performed on mice to assess CoQ10's effects on fertility. After receiving CoQ10 for twelve to sixteen weeks, there was improvement of mitochondrial function markers and a higher number of eggs produced in older mice. These mice also produced more offspring. 

However, these improvements were only seen in older mice, not younger ones. More than that, humans and mice are very different. A human would have to take CoQ10 for ten years to match the amount of time the mice received the supplement. 

CoQ10 Studies in Humans

Additionally, there have only been a few small studies performed with humans before or during IVF treatment. Only five higher-quality studies have been done, with a total of 449 women. Only two of these studies considered the live birth rate. 

Ultimately, no studies have shown that CoQ10 taken before or during IVF increases the chances of having a live birth. The bottom line is, there's no conclusive evidence that CoQ10 will improve your chances of becoming a parent when taken during IVF treatment.

Use Caution When Taking Supplements

It may seem harmless to take a supplement like CoQ10, just in case it might help. But it's important to be careful. CoQ10 is not regulated by the Food and Drug Administration (FDA), so you can never really be sure what you're getting. 

CoQ10 supplements can cause a slew of side effects, like insomnia, loss of appetite, abdominal pain, diarrhea, fatigue, or even liver damage. Also, harmful things like lead, arsenic, and mercury can contaminate supplements during the manufacturing process. 

It's always best to use caution when it comes to taking over-the-counter supplements like CoQ10. It's wise to consult a fertility specialist first. They can help assess the root cause of the issue and come up with a unique treatment plan that's right for you.

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