Progesterone is used during IVF to help prepare to uterus to receive an embryo. Progesterone supplements the body's natural production of the hormone progesterone, which is not sufficient when other IVF drugs are used. Like any drug, there are some potential complications from progesterone injections, as we will explore below.

‍Reasons for Using Progesterone

‍Progesterone is used during IVF to stimulate the development of endometrial tissue, which supports the embryo until the placenta develops. Progesterone increases the chances of the embryo implanting, and decreases the chances of early miscarriage. The body naturally produces progesterone, but because of the use of medications that prevent early ovulation, such as Lupron or Ganirelix, during IVF, that natural production is often times, not sufficient.In most cases, progesterone injections or vaginal progesterone are continued through the 11th week of gestation. If the woman is at an increased risk of miscarriage because of a history of miscarriage or other issues, then she may continue to take progesterone for a longer period of time.

Possible Side Effects of Progesterone Injections

Most side effects of progesterone injections are mild and temporary. Some of the most common side effects include:

• Pain or swelling at the injection site - common
• Nausea - rare
• Dizziness - rare
• Drowsiness - rare
• Vaginal dryness - rare
• Gaining or losing weight - rare

If these symptoms are severe or persistent, you should talk to your doctor about your symptoms. In rare cases, it is possible for more serious side effects to occur. Your doctor will instruct you about which side effects to look for and when you should contact the office about your symptoms. Rare but serious side effects include blood clots and allergic reaction to the oil suspension used in intramuscular injections.

‍Weighing the Risks and Benefits

‍There is a risk of side effects with progesterone, as with any drug. However, the most common side effects are rare and reversible, while serious side effects are rare. In addition, the drug is necessary to have a successful IVF cycle. Ultimately, your doctor is recommending progesterone because the benefits outweigh the risks in his medical opinion. However, each patient must decide for themselves whether or not they agree with that assessment. The experts at IVF1 would be happy to meet with you about your fertility. To schedule your consultation today, please click below and enter your information or call us at (630) 357-6540.